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Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival

BACKGROUND: Hip fractures are associated with increased cerebrovascular accidents (CVAs) in the first postoperative year. Long-term follow-up for CVA and mortality after hip fracture is lacking. The purpose of this study was to identify risk factors for CVA and follow mortality in hip fractures in a...

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Autores principales: Atzmon, Ran, Sharfman, Zachary T., Efrati, Noa, Shohat, Noam, Brin, Yaron, Hetsroni, Iftach, Nyska, Meir, Palmanovich, Ezequiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027793/
https://www.ncbi.nlm.nih.gov/pubmed/29954421
http://dx.doi.org/10.1186/s13018-018-0867-1
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author Atzmon, Ran
Sharfman, Zachary T.
Efrati, Noa
Shohat, Noam
Brin, Yaron
Hetsroni, Iftach
Nyska, Meir
Palmanovich, Ezequiel
author_facet Atzmon, Ran
Sharfman, Zachary T.
Efrati, Noa
Shohat, Noam
Brin, Yaron
Hetsroni, Iftach
Nyska, Meir
Palmanovich, Ezequiel
author_sort Atzmon, Ran
collection PubMed
description BACKGROUND: Hip fractures are associated with increased cerebrovascular accidents (CVAs) in the first postoperative year. Long-term follow-up for CVA and mortality after hip fracture is lacking. The purpose of this study was to identify risk factors for CVA and follow mortality in hip fractures in a cohort with greater than 2 years follow-up. METHODS: We compared past medical history of patients with hip fractures to long-term survival and the occurrence of CVA. Past medical history, surgical intervention, CVA occurrence, and death were queried from the electronic medical recorder system. Level of significance was set at p < 0.05 with 95% confidence interval. RESULTS: Two thousand one hundred ninety-five patients met inclusion criteria. Mean follow-up was 5 years. One hundred ten (5.01%) patients were diagnosed with post-fracture CVA. Forty-one patients had CVA in the first year and 55 patients had CVA between 1 to 5 years after surgery. Among the potential risk factors, hypertension (HTN), atrial fibrillation (AF), and diabetes mellitus (DM) had the highest odds ratio for CVA (OR = 1.885, p value = 0.005; OR = 1.79, p value = 0.012; OR = 1.66, p value = 0.012). The median survival time in patients with CVA was 51.12 ± 3.76 months compared to 59.60 ± 0.93 months in patients without CVA (p = 0.033). CONCLUSIONS: HTN, AF, and DM are significant risk factors for the occurrence of CVA after hip fracture. The majority of CVAs occur between the first and fifth year postoperatively, and CVA is a negative prognostic factor for postoperative survival.
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spelling pubmed-60277932018-07-09 Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival Atzmon, Ran Sharfman, Zachary T. Efrati, Noa Shohat, Noam Brin, Yaron Hetsroni, Iftach Nyska, Meir Palmanovich, Ezequiel J Orthop Surg Res Research Article BACKGROUND: Hip fractures are associated with increased cerebrovascular accidents (CVAs) in the first postoperative year. Long-term follow-up for CVA and mortality after hip fracture is lacking. The purpose of this study was to identify risk factors for CVA and follow mortality in hip fractures in a cohort with greater than 2 years follow-up. METHODS: We compared past medical history of patients with hip fractures to long-term survival and the occurrence of CVA. Past medical history, surgical intervention, CVA occurrence, and death were queried from the electronic medical recorder system. Level of significance was set at p < 0.05 with 95% confidence interval. RESULTS: Two thousand one hundred ninety-five patients met inclusion criteria. Mean follow-up was 5 years. One hundred ten (5.01%) patients were diagnosed with post-fracture CVA. Forty-one patients had CVA in the first year and 55 patients had CVA between 1 to 5 years after surgery. Among the potential risk factors, hypertension (HTN), atrial fibrillation (AF), and diabetes mellitus (DM) had the highest odds ratio for CVA (OR = 1.885, p value = 0.005; OR = 1.79, p value = 0.012; OR = 1.66, p value = 0.012). The median survival time in patients with CVA was 51.12 ± 3.76 months compared to 59.60 ± 0.93 months in patients without CVA (p = 0.033). CONCLUSIONS: HTN, AF, and DM are significant risk factors for the occurrence of CVA after hip fracture. The majority of CVAs occur between the first and fifth year postoperatively, and CVA is a negative prognostic factor for postoperative survival. BioMed Central 2018-06-28 /pmc/articles/PMC6027793/ /pubmed/29954421 http://dx.doi.org/10.1186/s13018-018-0867-1 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Atzmon, Ran
Sharfman, Zachary T.
Efrati, Noa
Shohat, Noam
Brin, Yaron
Hetsroni, Iftach
Nyska, Meir
Palmanovich, Ezequiel
Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title_full Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title_fullStr Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title_full_unstemmed Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title_short Cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
title_sort cerebrovascular accidents associated with hip fractures: morbidity and mortality—5-year survival
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027793/
https://www.ncbi.nlm.nih.gov/pubmed/29954421
http://dx.doi.org/10.1186/s13018-018-0867-1
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