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Genetic Analyses of Elys Mutations in Drosophila Show Maternal-Effect Lethality and Interactions with Nucleoporin Genes
ELYS determines the subcellular localizations of Nucleoporins (Nups) during interphase and mitosis. We made loss-of-function mutations of Elys in Drosophila melanogaster and found that ELYS is dispensable for zygotic viability and male fertility but the maternal supply is necessary for embryonic dev...
Autores principales: | Hirai, Kazuyuki, Wang, Zhuo, Miura, Kohei, Hayashi, Takaaki, Awasaki, Takeshi, Wada, Moe, Keira, Yoko, Ishikawa, Hiroyuki O., Sawamura, Kyoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027884/ https://www.ncbi.nlm.nih.gov/pubmed/29773558 http://dx.doi.org/10.1534/g3.118.200361 |
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