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Genetic Analyses of Elys Mutations in Drosophila Show Maternal-Effect Lethality and Interactions with Nucleoporin Genes

ELYS determines the subcellular localizations of Nucleoporins (Nups) during interphase and mitosis. We made loss-of-function mutations of Elys in Drosophila melanogaster and found that ELYS is dispensable for zygotic viability and male fertility but the maternal supply is necessary for embryonic dev...

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Detalles Bibliográficos
Autores principales: Hirai, Kazuyuki, Wang, Zhuo, Miura, Kohei, Hayashi, Takaaki, Awasaki, Takeshi, Wada, Moe, Keira, Yoko, Ishikawa, Hiroyuki O., Sawamura, Kyoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027884/
https://www.ncbi.nlm.nih.gov/pubmed/29773558
http://dx.doi.org/10.1534/g3.118.200361

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