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Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these...

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Detalles Bibliográficos
Autores principales: Burns, Michael B., Montassier, Emmanuel, Abrahante, Juan, Priya, Sambhawa, Niccum, David E., Khoruts, Alexander, Starr, Timothy K., Knights, Dan, Blekhman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028121/
https://www.ncbi.nlm.nih.gov/pubmed/29924794
http://dx.doi.org/10.1371/journal.pgen.1007376

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