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Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment
Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these...
Autores principales: | Burns, Michael B., Montassier, Emmanuel, Abrahante, Juan, Priya, Sambhawa, Niccum, David E., Khoruts, Alexander, Starr, Timothy K., Knights, Dan, Blekhman, Ran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028121/ https://www.ncbi.nlm.nih.gov/pubmed/29924794 http://dx.doi.org/10.1371/journal.pgen.1007376 |
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