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Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing
N6-Methyladenine (m(6)dA) has been discovered as a novel form of DNA methylation prevalent in eukaryotes; however, methods for high-resolution mapping of m(6)dA events are still lacking. Single-molecule real-time (SMRT) sequencing has enabled the detection of m(6)dA events at single-nucleotide resol...
Autores principales: | Zhu, Shijia, Beaulaurier, John, Deikus, Gintaras, Wu, Tao P., Strahl, Maya, Hao, Ziyang, Luo, Guanzheng, Gregory, James A., Chess, Andrew, He, Chuan, Xiao, Andrew, Sebra, Robert, Schadt, Eric E., Fang, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028124/ https://www.ncbi.nlm.nih.gov/pubmed/29764913 http://dx.doi.org/10.1101/gr.231068.117 |
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