Cargando…

Modeling leaderless transcription and atypical genes results in more accurate gene prediction in prokaryotes

In a conventional view of the prokaryotic genome organization, promoters precede operons and ribosome binding sites (RBSs) with Shine-Dalgarno consensus precede genes. However, recent experimental research suggesting a more diverse view motivated us to develop an algorithm with improved gene-finding...

Descripción completa

Detalles Bibliográficos
Autores principales: Lomsadze, Alexandre, Gemayel, Karl, Tang, Shiyuyun, Borodovsky, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028130/
https://www.ncbi.nlm.nih.gov/pubmed/29773659
http://dx.doi.org/10.1101/gr.230615.117