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Modeling leaderless transcription and atypical genes results in more accurate gene prediction in prokaryotes
In a conventional view of the prokaryotic genome organization, promoters precede operons and ribosome binding sites (RBSs) with Shine-Dalgarno consensus precede genes. However, recent experimental research suggesting a more diverse view motivated us to develop an algorithm with improved gene-finding...
Autores principales: | Lomsadze, Alexandre, Gemayel, Karl, Tang, Shiyuyun, Borodovsky, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028130/ https://www.ncbi.nlm.nih.gov/pubmed/29773659 http://dx.doi.org/10.1101/gr.230615.117 |
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