ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes

We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA. We suggest further genetic investigation for patients presenting with severe hypertriglyceridemia...

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Detalles Bibliográficos
Autores principales: Keefe, Christel, Lawson, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028359/
https://www.ncbi.nlm.nih.gov/pubmed/29988659
http://dx.doi.org/10.1002/ccr3.1584
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author Keefe, Christel
Lawson, Sarah
author_facet Keefe, Christel
Lawson, Sarah
author_sort Keefe, Christel
collection PubMed
description We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA. We suggest further genetic investigation for patients presenting with severe hypertriglyceridemia and DKA.
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spelling pubmed-60283592018-07-09 ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes Keefe, Christel Lawson, Sarah Clin Case Rep Case Reports We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA. We suggest further genetic investigation for patients presenting with severe hypertriglyceridemia and DKA. John Wiley and Sons Inc. 2018-05-24 /pmc/articles/PMC6028359/ /pubmed/29988659 http://dx.doi.org/10.1002/ccr3.1584 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Keefe, Christel
Lawson, Sarah
ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title_full ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title_fullStr ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title_full_unstemmed ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title_short ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
title_sort apoe isoform leading to hypertriglyceridemia in new onset type 1 diabetes
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028359/
https://www.ncbi.nlm.nih.gov/pubmed/29988659
http://dx.doi.org/10.1002/ccr3.1584
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AT lawsonsarah apoeisoformleadingtohypertriglyceridemiainnewonsettype1diabetes

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