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External K(+) dependence of strong inward rectifier K(+) channel conductance is caused not by K(+) but by competitive pore blockade by external Na(+)
Strong inward rectifier K(+) (sKir) channels determine the membrane potentials of many types of excitable and nonexcitable cells, most notably the resting potentials of cardiac myocytes. They show little outward current during membrane depolarization (i.e., strong inward rectification) because of th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028490/ https://www.ncbi.nlm.nih.gov/pubmed/29907600 http://dx.doi.org/10.1085/jgp.201711936 |