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Known structures and unknown mechanisms of TMEM16 scramblases and channels
The TMEM16 family of membrane proteins is composed of both Ca(2+)-gated Cl(−) channels and Ca(2+)-dependent phospholipid scramblases. The functional diversity of TMEM16s underlies their involvement in numerous signal transduction pathways that connect changes in cytosolic Ca(2+) levels to cellular s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028493/ https://www.ncbi.nlm.nih.gov/pubmed/29915161 http://dx.doi.org/10.1085/jgp.201711957 |