Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function

The volume-regulated anion channel (VRAC) is expressed ubiquitously in vertebrate cells and mediates swelling-induced release of Cl(−) and organic solutes. Recent studies by several laboratories have demonstrated conclusively that VRAC is encoded by members of the leucine-rich repeat containing 8 (L...

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Detalles Bibliográficos
Autores principales: Yamada, Toshiki, Strange, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028502/
https://www.ncbi.nlm.nih.gov/pubmed/29853476
http://dx.doi.org/10.1085/jgp.201812016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028502/
https://www.ncbi.nlm.nih.gov/pubmed/29853476
http://dx.doi.org/10.1085/jgp.201812016

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