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The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8(+) T cells
T cells are actively scanning pMHC-presenting cells in lymphoid organs and nonlymphoid tissues (NLTs) with divergent topologies and confinement. How the T cell actomyosin cytoskeleton facilitates this task in distinct environments is incompletely understood. Here, we show that lack of Myosin IXb (My...
Autores principales: | Moalli, Federica, Ficht, Xenia, Germann, Philipp, Vladymyrov, Mykhailo, Stolp, Bettina, de Vries, Ingrid, Lyck, Ruth, Balmer, Jasmin, Fiocchi, Amleto, Kreutzfeldt, Mario, Merkler, Doron, Iannacone, Matteo, Ariga, Akitaka, Stoffel, Michael H., Sharpe, James, Bähler, Martin, Sixt, Michael, Diz-Muñoz, Alba, Stein, Jens V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028505/ https://www.ncbi.nlm.nih.gov/pubmed/29875261 http://dx.doi.org/10.1084/jem.20170896 |
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