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TRIMming TGF-β signals in Th17 cells
The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028513/ https://www.ncbi.nlm.nih.gov/pubmed/29945999 http://dx.doi.org/10.1084/jem.20180986 |
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author | Rapaport, Aaron S. Ouyang, Wenjun |
author_facet | Rapaport, Aaron S. Ouyang, Wenjun |
author_sort | Rapaport, Aaron S. |
collection | PubMed |
description | The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile. |
format | Online Article Text |
id | pubmed-6028513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60285132019-01-02 TRIMming TGF-β signals in Th17 cells Rapaport, Aaron S. Ouyang, Wenjun J Exp Med News The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile. Rockefeller University Press 2018-07-02 /pmc/articles/PMC6028513/ /pubmed/29945999 http://dx.doi.org/10.1084/jem.20180986 Text en © 2018 Ouyang and Rapaport http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | News Rapaport, Aaron S. Ouyang, Wenjun TRIMming TGF-β signals in Th17 cells |
title | TRIMming TGF-β signals in Th17 cells |
title_full | TRIMming TGF-β signals in Th17 cells |
title_fullStr | TRIMming TGF-β signals in Th17 cells |
title_full_unstemmed | TRIMming TGF-β signals in Th17 cells |
title_short | TRIMming TGF-β signals in Th17 cells |
title_sort | trimming tgf-β signals in th17 cells |
topic | News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028513/ https://www.ncbi.nlm.nih.gov/pubmed/29945999 http://dx.doi.org/10.1084/jem.20180986 |
work_keys_str_mv | AT rapaportaarons trimmingtgfbsignalsinth17cells AT ouyangwenjun trimmingtgfbsignalsinth17cells |