Cargando…

TRIMming TGF-β signals in Th17 cells

The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile.

Detalles Bibliográficos
Autores principales: Rapaport, Aaron S., Ouyang, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028513/
https://www.ncbi.nlm.nih.gov/pubmed/29945999
http://dx.doi.org/10.1084/jem.20180986
_version_ 1783336778918264832
author Rapaport, Aaron S.
Ouyang, Wenjun
author_facet Rapaport, Aaron S.
Ouyang, Wenjun
author_sort Rapaport, Aaron S.
collection PubMed
description The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile.
format Online
Article
Text
id pubmed-6028513
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-60285132019-01-02 TRIMming TGF-β signals in Th17 cells Rapaport, Aaron S. Ouyang, Wenjun J Exp Med News The precise downstream mediators of TGF-β signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-β signals in Th17 cells to generate an optimal proinflammatory cytokine profile. Rockefeller University Press 2018-07-02 /pmc/articles/PMC6028513/ /pubmed/29945999 http://dx.doi.org/10.1084/jem.20180986 Text en © 2018 Ouyang and Rapaport http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Rapaport, Aaron S.
Ouyang, Wenjun
TRIMming TGF-β signals in Th17 cells
title TRIMming TGF-β signals in Th17 cells
title_full TRIMming TGF-β signals in Th17 cells
title_fullStr TRIMming TGF-β signals in Th17 cells
title_full_unstemmed TRIMming TGF-β signals in Th17 cells
title_short TRIMming TGF-β signals in Th17 cells
title_sort trimming tgf-β signals in th17 cells
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028513/
https://www.ncbi.nlm.nih.gov/pubmed/29945999
http://dx.doi.org/10.1084/jem.20180986
work_keys_str_mv AT rapaportaarons trimmingtgfbsignalsinth17cells
AT ouyangwenjun trimmingtgfbsignalsinth17cells