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Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP
The massive dynein motor complexes that drive ciliary and flagellar motility require cytoplasmic preassembly, a process requiring dedicated dynein assembly factors (DNAAFs). How DNAAFs interact with molecular chaperones to control dynein assembly is not clear. By analogy with the well-known multifun...
Autores principales: | zur Lage, Petra, Stefanopoulou, Panagiota, Styczynska-Soczka, Katarzyna, Quinn, Niall, Mali, Girish, von Kriegsheim, Alex, Mill, Pleasantine, Jarman, Andrew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028525/ https://www.ncbi.nlm.nih.gov/pubmed/29743191 http://dx.doi.org/10.1083/jcb.201709026 |
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