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Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules

Microtubules (MTs) must be generated from precise locations to form the structural frameworks required for cell shape and function. MTs are nucleated by the γ-tubulin ring complex (γ-TuRC), but it remains unclear how γ-TuRC gets to the right location. Augmin has been suggested to be a γ-TuRC targeti...

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Detalles Bibliográficos
Autores principales: Song, Jae-Geun, King, Matthew R., Zhang, Rui, Kadzik, Rachel S., Thawani, Akanksha, Petry, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028527/
https://www.ncbi.nlm.nih.gov/pubmed/29875259
http://dx.doi.org/10.1083/jcb.201711090