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A quantitative map of human Condensins provides new insights into mitotic chromosome architecture

The two Condensin complexes in human cells are essential for mitotic chromosome structure. We used homozygous genome editing to fluorescently tag Condensin I and II subunits and mapped their absolute abundance, spacing, and dynamic localization during mitosis by fluorescence correlation spectroscopy...

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Detalles Bibliográficos
Autores principales:	Walther, Nike, Hossain, M. Julius, Politi, Antonio Z., Koch, Birgit, Kueblbeck, Moritz, Ødegård-Fougner, Øyvind, Lampe, Marko, Ellenberg, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028534/ https://www.ncbi.nlm.nih.gov/pubmed/29632028 http://dx.doi.org/10.1083/jcb.201801048

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