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HRS–WASH axis governs actin-mediated endosomal recycling and cell invasion
Transmembrane proteins in the sorting endosome are either recycled to their point of origin or destined for lysosomal degradation. Lysosomal sorting is mediated by interaction of ubiquitylated transmembrane proteins with the endosomal sorting complex required for transport (ESCRT) machinery. In this...
Autores principales: | MacDonald, Ewan, Brown, Louise, Selvais, Arnaud, Liu, Han, Waring, Thomas, Newman, Daniel, Bithell, Jessica, Grimes, Douglas, Urbé, Sylvie, Clague, Michael J., Zech, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028553/ https://www.ncbi.nlm.nih.gov/pubmed/29891722 http://dx.doi.org/10.1083/jcb.201710051 |
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