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A Canonical Biophysical Model of the CsrA Global Regulator Suggests Flexible Regulator-Target Interactions

Bacterial global post-transcriptional regulators execute hundreds of interactions with targets that display varying molecular features while retaining specificity. Herein, we develop, validate, and apply a biophysical, statistical thermodynamic model of canonical target mRNA interactions with the Cs...

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Detalles Bibliográficos
Autores principales: Leistra, A. N., Gelderman, G., Sowa, S. W., Moon-Walker, A., Salis, H. M., Contreras, L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028588/
https://www.ncbi.nlm.nih.gov/pubmed/29967470
http://dx.doi.org/10.1038/s41598-018-27474-2

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