Cargando…
New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy
Small molecules that deter the functions of DNA damage response machinery are postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing radiation treatments to combat cancer by impairing the proliferative capacity of rapidly dividing cells that accumulate replicative...
Autores principales: | Datta, Arindam, Brosh, Robert M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028597/ https://www.ncbi.nlm.nih.gov/pubmed/29998112 http://dx.doi.org/10.3389/fmolb.2018.00059 |
Ejemplares similares
-
Single-Molecule Insights Into the Dynamics of Replicative Helicases
por: Spinks, Richard R., et al.
Publicado: (2021) -
The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy
por: Seo, Yeon-Soo, et al.
Publicado: (2018) -
Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase
por: Zhang, Bo, et al.
Publicado: (2022) -
RecQ Helicase Somatic Alterations in Cancer
por: Thakkar, Megha K., et al.
Publicado: (2022) -
Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations
por: Mohd Yunos, Ryia Illani, et al.
Publicado: (2023)