The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy

Sodium polystyrene sulfonate (SPS: Kayexalate(Ⓡ)) is an ion-exchange resin used to treat hyperkalemia in patients with chronic kidney disease. It is known that this resin sometimes causes colonic necrosis and perforation, but there are few reports about small bowel necrosis associated with SPS. We h...

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Autores principales: Okayama, Kohei, Hirata, Yoshikazu, Kumai, Daisuke, Yamamoto, Yuki, Kojima, Yuki, Kanno, Takuya, Ikeuchi, Hirokazu, Mochizuki, Hisato, Takada, Hiroki, Sobue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028675/
https://www.ncbi.nlm.nih.gov/pubmed/29321412
http://dx.doi.org/10.2169/internalmedicine.0088-17
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author Okayama, Kohei
Hirata, Yoshikazu
Kumai, Daisuke
Yamamoto, Yuki
Kojima, Yuki
Kanno, Takuya
Ikeuchi, Hirokazu
Mochizuki, Hisato
Takada, Hiroki
Sobue, Satoshi
author_facet Okayama, Kohei
Hirata, Yoshikazu
Kumai, Daisuke
Yamamoto, Yuki
Kojima, Yuki
Kanno, Takuya
Ikeuchi, Hirokazu
Mochizuki, Hisato
Takada, Hiroki
Sobue, Satoshi
author_sort Okayama, Kohei
collection PubMed
description Sodium polystyrene sulfonate (SPS: Kayexalate(Ⓡ)) is an ion-exchange resin used to treat hyperkalemia in patients with chronic kidney disease. It is known that this resin sometimes causes colonic necrosis and perforation, but there are few reports about small bowel necrosis associated with SPS. We herein report the case of a patient who developed SPS-induced small bowel necrosis, which was diagnosed based on the examination of a small bowel endoscopic biopsy specimen. The SPS-induced small bowel necrosis was resistant to conservative treatment including the cessation of SPS, and finally required surgical bowel resection.
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spelling pubmed-60286752018-07-03 The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy Okayama, Kohei Hirata, Yoshikazu Kumai, Daisuke Yamamoto, Yuki Kojima, Yuki Kanno, Takuya Ikeuchi, Hirokazu Mochizuki, Hisato Takada, Hiroki Sobue, Satoshi Intern Med Case Report Sodium polystyrene sulfonate (SPS: Kayexalate(Ⓡ)) is an ion-exchange resin used to treat hyperkalemia in patients with chronic kidney disease. It is known that this resin sometimes causes colonic necrosis and perforation, but there are few reports about small bowel necrosis associated with SPS. We herein report the case of a patient who developed SPS-induced small bowel necrosis, which was diagnosed based on the examination of a small bowel endoscopic biopsy specimen. The SPS-induced small bowel necrosis was resistant to conservative treatment including the cessation of SPS, and finally required surgical bowel resection. The Japanese Society of Internal Medicine 2018-01-11 2018-06-01 /pmc/articles/PMC6028675/ /pubmed/29321412 http://dx.doi.org/10.2169/internalmedicine.0088-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Okayama, Kohei
Hirata, Yoshikazu
Kumai, Daisuke
Yamamoto, Yuki
Kojima, Yuki
Kanno, Takuya
Ikeuchi, Hirokazu
Mochizuki, Hisato
Takada, Hiroki
Sobue, Satoshi
The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title_full The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title_fullStr The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title_full_unstemmed The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title_short The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy
title_sort successful treatment of sodium polystyrene sulfonate-induced enteritis diagnosed by small bowel endoscopy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028675/
https://www.ncbi.nlm.nih.gov/pubmed/29321412
http://dx.doi.org/10.2169/internalmedicine.0088-17
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