Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography

We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost a...

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Detalles Bibliográficos
Autores principales: Higuchi, Yoshihiro, Kimoto, Yasutaka, Tanoue, Rika, Tokunou, Tomotake, Tomonari, Kenichiro, Maeda, Toyoki, Horiuchi, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028683/
https://www.ncbi.nlm.nih.gov/pubmed/29321427
http://dx.doi.org/10.2169/internalmedicine.9652-17
Descripción
Sumario:We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.

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