Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography

We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost a...

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Autores principales: Higuchi, Yoshihiro, Kimoto, Yasutaka, Tanoue, Rika, Tokunou, Tomotake, Tomonari, Kenichiro, Maeda, Toyoki, Horiuchi, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028683/
https://www.ncbi.nlm.nih.gov/pubmed/29321427
http://dx.doi.org/10.2169/internalmedicine.9652-17
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author Higuchi, Yoshihiro
Kimoto, Yasutaka
Tanoue, Rika
Tokunou, Tomotake
Tomonari, Kenichiro
Maeda, Toyoki
Horiuchi, Takahiko
author_facet Higuchi, Yoshihiro
Kimoto, Yasutaka
Tanoue, Rika
Tokunou, Tomotake
Tomonari, Kenichiro
Maeda, Toyoki
Horiuchi, Takahiko
author_sort Higuchi, Yoshihiro
collection PubMed
description We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.
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spelling pubmed-60286832018-07-03 Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography Higuchi, Yoshihiro Kimoto, Yasutaka Tanoue, Rika Tokunou, Tomotake Tomonari, Kenichiro Maeda, Toyoki Horiuchi, Takahiko Intern Med Case Report We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy. The Japanese Society of Internal Medicine 2018-01-11 2018-06-01 /pmc/articles/PMC6028683/ /pubmed/29321427 http://dx.doi.org/10.2169/internalmedicine.9652-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Higuchi, Yoshihiro
Kimoto, Yasutaka
Tanoue, Rika
Tokunou, Tomotake
Tomonari, Kenichiro
Maeda, Toyoki
Horiuchi, Takahiko
Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title_full Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title_fullStr Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title_full_unstemmed Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title_short Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by (18)F-fluorodeoxyglucose Positron Emission Tomography
title_sort cardiac sarcoidosis concomitant with large-vessel aortitis detected by (18)f-fluorodeoxyglucose positron emission tomography
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028683/
https://www.ncbi.nlm.nih.gov/pubmed/29321427
http://dx.doi.org/10.2169/internalmedicine.9652-17
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