Cargando…
Effect of maternal hypothyroidism during pregnancy on insulin resistance, lipid accumulation, and mitochondrial dysfunction in skeletal muscle of fetal rats
The present study aimed to investigate the effect of maternal hypothyroidism during pregnancy on thyroid function of the fetal rat. Female Sprague–Dawley rats were randomized into two groups. Propylthiouracil (PTU) group received PTU in drinking water for 6 weeks (n=90), normal group received normal...
Autores principales: | Xia, Tongjia, Zhang, Xue, Wang, Youmin, Deng, Datong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028760/ https://www.ncbi.nlm.nih.gov/pubmed/29784871 http://dx.doi.org/10.1042/BSR20171731 |
Ejemplares similares
-
Effect of hypothyroidism on the hypothalamic–pituitary–ovarian axis and reproductive function of pregnant rats
por: Sun, Jianran, et al.
Publicado: (2018) -
Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle
por: Chursa, Urszula, et al.
Publicado: (2016) -
Excess Accumulation of Lipid Impairs Insulin Sensitivity in Skeletal Muscle
por: Park, Sung Sup, et al.
Publicado: (2020) -
Moderately decreased maternal dietary energy intake during pregnancy reduces fetal skeletal muscle mitochondrial biogenesis in the pigs
por: Zou, Tiande, et al.
Publicado: (2016) -
Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice
por: Lee, Hyunjung, et al.
Publicado: (2021)