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Synthesis and in vitro antimicrobial activity screening of new pipemidic acid derivatives

ABSTRACT: This article describes the synthesis and antimicrobial activity evaluation of new pipemidic acid derivatives. New compounds were obtained on the basis of Mannich reaction of 4,5-disubstituted 1,2,4-triazole-3-thiones with pipemidic acid. Antimicrobial tests revealed high antibacterial acti...

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Detalles Bibliográficos
Autores principales: Popiołek, Łukasz, Biernasiuk, Anna, Paruch, Kinga, Malm, Anna, Wujec, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028826/
https://www.ncbi.nlm.nih.gov/pubmed/29619676
http://dx.doi.org/10.1007/s12272-018-1025-3