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Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation
Gene transcription is carried out by multi-subunit RNA polymerases (RNAPs). Transcription initiation is a dynamic multi-step process that involves the opening of the double-stranded DNA to form a transcription bubble and delivery of the template strand deep into the RNAP for RNA synthesis. Applying...
Autores principales: | Glyde, Robert, Ye, Fuzhou, Jovanovic, Milija, Kotta-Loizou, Ioly, Buck, Martin, Zhang, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028918/ https://www.ncbi.nlm.nih.gov/pubmed/29932903 http://dx.doi.org/10.1016/j.molcel.2018.05.021 |
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