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Cornel Iridoid Glycoside Inhibits Tau Hyperphosphorylation via Regulating Cross-Talk Between GSK-3β and PP2A Signaling

Neurofibrillary pathology contributes to neuronal dysfunction and correlates with the clinical progression of Alzheimer’s disease (AD). Tau phosphorylation is mainly regulated by a balance of glycogen synthase kinase-3β (GSK-3β) and protein phosphatase 2A (PP2A) activities. Cornel iridoid glycoside...

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Detalles Bibliográficos
Autores principales:	Yang, Cuicui, Li, Xuelian, Gao, Wenbin, Wang, Qi, Zhang, Li, Li, Yali, Li, Lin, Zhang, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028923/ https://www.ncbi.nlm.nih.gov/pubmed/29997510 http://dx.doi.org/10.3389/fphar.2018.00682

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