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Mechanism of vaccinia viral protein B14–mediated inhibition of IκB kinase β activation

Activation of IκB kinase β (IKKβ) is a central event in the NF-κB–mediated canonical pro-inflammatory pathway. Numerous studies have reported that oligomerization-mediated trans autophosphorylation of IKKβ is indispensable for its phosphorylation, leading to its activation and IKKβ-mediated phosphor...

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Detalles Bibliográficos
Autores principales:	Tang, Qingyu, Chakraborty, Sayan, Xu, Guozhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028965/ https://www.ncbi.nlm.nih.gov/pubmed/29748387 http://dx.doi.org/10.1074/jbc.RA118.002817

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