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CD8(+) T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication
BACKGROUND: Development of AIDS vaccines for effective prevention of circulating HIV-1 is required, but no trial has demonstrated definitive effects on the prevention. Several recent T-cell vaccine trials showed no protection against HIV-1 acquisition although the vaccines induced HIV-1-specific T-c...
Autores principales: | Murakoshi, Hayato, Zou, Chengcheng, Kuse, Nozomi, Akahoshi, Tomohiro, Chikata, Takayuki, Gatanaga, Hiroyuki, Oka, Shinichi, Hanke, Tomáš, Takiguchi, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029025/ https://www.ncbi.nlm.nih.gov/pubmed/29970102 http://dx.doi.org/10.1186/s12977-018-0429-y |
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