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Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway

BACKGROUND: Fascin is a F-actin bundling protein and its overexpression is correlated with poor prognosis and increases metastatic potential in a number of cancers. But underlying function and mechanism of fascin on tumorigenesis in melanoma remain elusive. METHODS: The melanoma cell lines WM793 and...

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Detalles Bibliográficos
Autores principales: Kang, Jiaxin, Wang, Jian, Yao, Zhuang, Hu, Yuanzhao, Ma, Shijie, Fan, Qin, Gao, Feng, Sun, Yan, Sun, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029074/
https://www.ncbi.nlm.nih.gov/pubmed/29970086
http://dx.doi.org/10.1186/s12964-018-0250-1

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