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Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway
BACKGROUND: Fascin is a F-actin bundling protein and its overexpression is correlated with poor prognosis and increases metastatic potential in a number of cancers. But underlying function and mechanism of fascin on tumorigenesis in melanoma remain elusive. METHODS: The melanoma cell lines WM793 and...
Autores principales: | Kang, Jiaxin, Wang, Jian, Yao, Zhuang, Hu, Yuanzhao, Ma, Shijie, Fan, Qin, Gao, Feng, Sun, Yan, Sun, Jianwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029074/ https://www.ncbi.nlm.nih.gov/pubmed/29970086 http://dx.doi.org/10.1186/s12964-018-0250-1 |
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