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Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum

BACKGROUND: According to the traditional tuberculosis (TB) treatment paradigm, the initial doses of treatment rapidly kill most Mycobacterium tuberculosis (Mtb) bacilli in sputum, yet many more months of daily treatment are required to eliminate a small, residual subpopulation of drug-tolerant bacil...

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Detalles Bibliográficos
Autores principales:	Walter, Nicholas D., Moore, Camille M., Kayigire, Xavier A., Dide-Agossou, Christian, Worodria, William, Huang, Laurence, Everett, Charles K., Schoolnik, Gary S., Nahid, Payam, Lucian Davis, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029172/ https://www.ncbi.nlm.nih.gov/pubmed/29970012 http://dx.doi.org/10.1186/s12879-018-3213-7

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