Alzheimer Disease and Selected Risk Factors Disrupt a Co-regulation of Monoamine Oxidase-A/B in the Hippocampus, but Not in the Cortex

Monoamine oxidase-A (MAO-A) and MAO-B have both been implicated in the pathology of Alzheimer disease (AD). We examined 60 autopsied control and AD donor brain samples to determine how well MAO function aligned with two major risk factors for AD, namely sex and APOE ε4 status. MAO-A activity was inc...

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Detalles Bibliográficos
Autores principales: Quartey, Maa O., Nyarko, Jennifer N. K., Pennington, Paul R., Heistad, Ryan M., Klassen, Paula C., Baker, Glen B., Mousseau, Darrell D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029266/
https://www.ncbi.nlm.nih.gov/pubmed/29997470
http://dx.doi.org/10.3389/fnins.2018.00419

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