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BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization

BACKGROUND: Variation in chromatin organization across single cells can help shed important light on the mechanisms controlling gene expression, but scale, noise, and sparsity pose significant challenges for interpretation of single cell chromatin data. Here, we develop BROCKMAN (Brockman Representa...

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Detalles Bibliográficos
Autores principales: de Boer, Carl G., Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029352/
https://www.ncbi.nlm.nih.gov/pubmed/29970004
http://dx.doi.org/10.1186/s12859-018-2255-6