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BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization
BACKGROUND: Variation in chromatin organization across single cells can help shed important light on the mechanisms controlling gene expression, but scale, noise, and sparsity pose significant challenges for interpretation of single cell chromatin data. Here, we develop BROCKMAN (Brockman Representa...
Autores principales: | de Boer, Carl G., Regev, Aviv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029352/ https://www.ncbi.nlm.nih.gov/pubmed/29970004 http://dx.doi.org/10.1186/s12859-018-2255-6 |
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