Cargando…

Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons

The muscarinic acetylcholine type 1 receptor (M(1)R) is a metabotropic G protein-coupled receptor. Knockout of M(1)R or exposure to selective or specific receptor antagonists elevates neurite outgrowth in adult sensory neurons and is therapeutic in diverse models of peripheral neuropathy. We tested...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sabbir, Mohammad G., Calcutt, Nigel A., Fernyhough, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029366/ https://www.ncbi.nlm.nih.gov/pubmed/29997469 http://dx.doi.org/10.3389/fnins.2018.00402

Ejemplares similares

GIT1 enhances neurite outgrowth by stimulating microtubule assembly
por: Li, Yi-sheng, et al.
Publicado: (2016)

Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons
por: Saleh, Ali, et al.
Publicado: (2013)

SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth
por: Li, Shaojin, et al.
Publicado: (2022)

Neurite outgrowth is driven by actin polymerization even in the presence of actin polymerization inhibitors
por: Chia, Jonathan X., et al.
Publicado: (2016)

Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding
por: Norkett, Rosalind, et al.
Publicado: (2020)

Dynamic balance between vesicle transport and microtubule growth enables neurite outgrowth
por: Yadaw, Arjun Singh, et al.
Publicado: (2019)

Muscarinic Toxin 7 Signals Via Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration
por: Saleh, Ali, et al.
Publicado: (2020)

The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
por: Kase, Yoshitaka, et al.
Publicado: (2022)

Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth
Publicado: (1986)

Mitochondrial Localized STAT3 Is Involved in NGF Induced Neurite Outgrowth
por: Zhou, Lihan, et al.
Publicado: (2011)

Antagonism of the Muscarinic Acetylcholine Type 1 Receptor Enhances Mitochondrial Membrane Potential and Expression of Respiratory Chain Components via AMPK in Human Neuroblastoma SH-SY5Y Cells and Primary Neurons
por: Naznin, Farhana, et al.
Publicado: (2022)

Neurite Outgrowth Inhibitors in Gliotic Tissue
por: Nieto-Sampedro, M., et al.
Publicado: (1992)

The impact of resource competition on neurite outgrowth
por: Hjorth, Johannes JJ, et al.
Publicado: (2011)

Proteoglycans: Road Signs for Neurite Outgrowth
por: Beller, Justin A., et al.
Publicado: (2014)

An Integrated Cytoskeletal Model of Neurite Outgrowth
por: Miller, Kyle E., et al.
Publicado: (2018)

Lactate transport facilitates neurite outgrowth
por: Chen, Kun, et al.
Publicado: (2018)

Ultrasonic control of neurite outgrowth direction
por: Maruyama, Haruki, et al.
Publicado: (2021)

Distinctive roles of Rac1 and Rab29 in LRRK2 mediated membrane trafficking and neurite outgrowth
por: Feng, Min, et al.
Publicado: (2018)

Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin
por: Hobson, Sally-Ann, et al.
Publicado: (2013)

Allosteric Modulation of Muscarinic Acetylcholine Receptors
por: Gregory, Karen J, et al.
Publicado: (2007)

Allosteric Modulation of Muscarinic Acetylcholine Receptors
por: Jakubík, Jan, et al.
Publicado: (2010)

Molecular properties of muscarinic acetylcholine receptors
por: HAGA, Tatsuya
Publicado: (2013)

Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates
por: Pedersen, Julia E., et al.
Publicado: (2018)

The regulation of mitochondrial dynamics in neurite outgrowth by retinoic acid receptor β signaling
por: Trigo, Diogo, et al.
Publicado: (2019)

Non-Neuronal Functions of the M(2) Muscarinic Acetylcholine Receptor
por: Ockenga, Wymke, et al.
Publicado: (2013)

Muscarinic acetylcholine receptor-dependent and NMDA receptor-dependent LTP and LTD share the common AMPAR trafficking pathway
por: Sumi, Tomonari, et al.
Publicado: (2023)

Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells
Publicado: (1985)

Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction
por: Sierra-Fonseca, Jorge A, et al.
Publicado: (2014)

Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability
por: Zhang, Yunlong, et al.
Publicado: (2023)

The Effects of Hematopoietic Growth Factors on Neurite Outgrowth
por: Su, Ye, et al.
Publicado: (2013)

Inducing Neurite Outgrowth by Mechanical Cell Stretch
por: Higgins, Suzanne, et al.
Publicado: (2013)

Releasing Nrf2 to promote neurite outgrowth
por: Yang, Chuanbin, et al.
Publicado: (2015)

The Role of Bioactive Compounds on the Promotion of Neurite Outgrowth
por: More, Sandeep Vasant, et al.
Publicado: (2012)

Role of Muscarinic Acetylcholine Signaling in Gastrointestinal Cancers
por: Konishi, Mitsuru, et al.
Publicado: (2019)

Muscarinic Acetylcholine Receptors in the Retina—Therapeutic Implications
por: Ruan, Yue, et al.
Publicado: (2021)

CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth
por: Aghanoori, Mohamad-Reza, et al.
Publicado: (2022)

γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells
por: Pišlar, Anja, et al.
Publicado: (2021)

Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation
por: Winans, Amy M, et al.
Publicado: (2016)

PC12 cells express juvenile microtubule-associated proteins during nerve growth factor-induced neurite outgrowth
Publicado: (1988)

Analysis of gene expression during neurite outgrowth and regeneration
por: Szpara, Moriah L, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_aqjgm4fkc2psod2g43f5d1c1fh