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Alternanthera mosaic potexvirus: Several Features, Properties, and Application
Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stab...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029478/ https://www.ncbi.nlm.nih.gov/pubmed/30018641 http://dx.doi.org/10.1155/2018/1973705 |
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author | Donchenko, Ekaterina Trifonova, Ekaterina Nikitin, Nikolai Atabekov, Joseph Karpova, Olga |
author_facet | Donchenko, Ekaterina Trifonova, Ekaterina Nikitin, Nikolai Atabekov, Joseph Karpova, Olga |
author_sort | Donchenko, Ekaterina |
collection | PubMed |
description | Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals. AltMV VLPs can assemble at various pH and ionic strengths. Furthermore, AltMV virions and VLPs demonstrate high immunogenicity, enhancing the immune response to the target antigen thus offering the possibility of being used as potential adjuvants. Recently, for the first time for plant viruses, we showed the structural difference between morphologically similar viral and virus-like particles on AltMV virions and VLPs. In this review, we discuss the features of AltMV virions, AltMV VLP assembly, and their structure and properties, as well as the characteristics of AltMV isolates, host plants, infection symptoms, AltMV isolation and purification, genome structure, viral proteins, and AltMV-based vectors. |
format | Online Article Text |
id | pubmed-6029478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-60294782018-07-17 Alternanthera mosaic potexvirus: Several Features, Properties, and Application Donchenko, Ekaterina Trifonova, Ekaterina Nikitin, Nikolai Atabekov, Joseph Karpova, Olga Adv Virol Review Article Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals. AltMV VLPs can assemble at various pH and ionic strengths. Furthermore, AltMV virions and VLPs demonstrate high immunogenicity, enhancing the immune response to the target antigen thus offering the possibility of being used as potential adjuvants. Recently, for the first time for plant viruses, we showed the structural difference between morphologically similar viral and virus-like particles on AltMV virions and VLPs. In this review, we discuss the features of AltMV virions, AltMV VLP assembly, and their structure and properties, as well as the characteristics of AltMV isolates, host plants, infection symptoms, AltMV isolation and purification, genome structure, viral proteins, and AltMV-based vectors. Hindawi 2018-06-19 /pmc/articles/PMC6029478/ /pubmed/30018641 http://dx.doi.org/10.1155/2018/1973705 Text en Copyright © 2018 Ekaterina Donchenko et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Donchenko, Ekaterina Trifonova, Ekaterina Nikitin, Nikolai Atabekov, Joseph Karpova, Olga Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title |
Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title_full |
Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title_fullStr |
Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title_full_unstemmed |
Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title_short |
Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
title_sort | alternanthera mosaic potexvirus: several features, properties, and application |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029478/ https://www.ncbi.nlm.nih.gov/pubmed/30018641 http://dx.doi.org/10.1155/2018/1973705 |
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