Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers

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Although outstanding progress has been made in understanding the pathophysiology of thrombotic thrombocytopenic purpura (TTP), knowledge of the immunopathogenesis of the disease is only at an early stage. Anti-ADAMTS13 auto-antibodies were shown to block proteolysis of von Willebrand factor and/or i...

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Detalles Bibliográficos
Autores principales: Hrdinová, Johana, D’Angelo, Silvia, Graça, Nuno A. G., Ercig, Bogac, Vanhoorelbeke, Karen, Veyradier, Agnès, Voorberg, Jan, Coppo, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029525/
https://www.ncbi.nlm.nih.gov/pubmed/29674502
http://dx.doi.org/10.3324/haematol.2016.151407
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