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Endothelin type A receptors mediate pain in a mouse model of sickle cell disease
Sickle cell disease is associated with acute painful episodes and chronic intractable pain. Endothelin-1, a known pain inducer, is elevated in the blood plasma of both sickle cell patients and mouse models of sickle cell disease. We show here that the levels of endothelin-1 and its endothelin type A...
Autores principales: | Lutz, Brianna Marie, Wu, Shaogen, Gu, Xiyao, Atianjoh, Fidelis E., Li, Zhen, Fox, Brandon M., Pollock, David M., Tao, Yuan-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029538/ https://www.ncbi.nlm.nih.gov/pubmed/29545351 http://dx.doi.org/10.3324/haematol.2017.187013 |
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