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Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers

INTRODUCTION: Mutations in the progranulin (GRN) gene are a major source of inherited frontotemporal degeneration (FTD) spectrum disorders associated with TDP-43 proteinopathy. We use structural MRI to identify regions of baseline differences and longitudinal changes in gray matter (GM) and white ma...

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Detalles Bibliográficos
Autores principales:	Olm, Christopher A., McMillan, Corey T., Irwin, David J., Van Deerlin, Vivianna M., Cook, Philip A., Gee, James C., Grossman, Murray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029561/ https://www.ncbi.nlm.nih.gov/pubmed/29984158 http://dx.doi.org/10.1016/j.nicl.2018.05.017

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