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Immunohistochemical assay for neuron-specific enolase, synaptophysin, and RB-associated protein as a diagnostic aid in advanced retinoblastomas

PURPOSE: We evaluated the expression of the neural markers, neuron-specific enolase, and synaptophysin, as a tool to confirm the diagnosis of retinoblastoma (RB) in undifferentiated and advanced tumors. Additionally, we determined whether the extent of RB-associated protein (pRb) expression is helpf...

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Detalles Bibliográficos
Autores principales: López López, José Carlos, Fernández Alonso, Nieves, Cuevas Álvarez, Juan, García-Caballero, Tomás, Pastor Jimeno, José Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029607/
https://www.ncbi.nlm.nih.gov/pubmed/29988700
http://dx.doi.org/10.2147/OPTH.S141503