Cargando…

IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β

Extracellular interleukin 1 alpha (IL-1α) released from keratinocytes is one of the endpoints for in vitro assessments of skin irritancy. Although cells dying via primary skin irritation undergo apoptosis as well as necrosis, IL-1α is not released in apoptotic cells. On the other hand, active secret...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hyejin, Cheong, Kyung Ah, Kim, Ji-Young, Kim, Nan-Hyung, Noh, Minsoo, Lee, Ai-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029682/ https://www.ncbi.nlm.nih.gov/pubmed/29310426 http://dx.doi.org/10.4062/biomolther.2017.167

Ejemplares similares

Intracellular IL-1 receptor antagonist (icIL-1Ra1) does not antagonize growth inhibitory effects of pre-IL-1α in SaOS-2 cells
por: Palmer, G, et al.
Publicado: (2005)

Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction
por: Lee, Hae-Ri, et al.
Publicado: (2023)

Eccrine Sweat Contains IL-1α, IL-1β and IL-31 and Activates Epidermal Keratinocytes as a Danger Signal
por: Dai, Xiuju, et al.
Publicado: (2013)

Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes
por: Tanaka, Yuka, et al.
Publicado: (2018)

IL-1 Receptor Antagonist (IL-1Ra) Levels and Management of Metabolic Disorders
por: Luotola, Kari
Publicado: (2022)

Influence of Polymorphism in the Genes for the Interleukin (IL)-1 Receptor Antagonist and IL-1β on Tuberculosis
por: Wilkinson, Robert J., et al.
Publicado: (1999)

The role of cytokines in seizures: interleukin (IL)-1β, IL-1Ra, IL-8, and IL-10
por: Youn, Youngah, et al.
Publicado: (2013)

Inhibition of Keratinocyte Differentiation by the Synergistic Effect of IL-17A, IL-22, IL-1α, TNFα and Oncostatin M
por: Rabeony, Hanitriniaina, et al.
Publicado: (2014)

Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8(+) T Cells, Resulting in Enhanced IL-1β Dependent Effector Function
por: Kim, Dong Hyun, et al.
Publicado: (2021)

IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice
por: Yoshizaki, Takamichi, et al.
Publicado: (2019)

Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion
por: Horai, Reiko, et al.
Publicado: (1998)

Three New Single Nucleotide Polymorphisms Identified by a Genome-Wide Association Study in Korean Patients with Vitiligo
por: Cheong, Kyung Ah, et al.
Publicado: (2013)

Rethinking IL-1 Antagonism in Respiratory Viral Infections: A Role for IL-1 Signaling in the Development of Antiviral T Cell Immunity
por: Van Den Eeckhout, Bram, et al.
Publicado: (2023)

A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6
por: Liao, Liping, et al.
Publicado: (2022)

IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA
por: Vastert, Sebastiaan J, et al.
Publicado: (2012)

Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody
Publicado: (1991)

Induction of Interleukin-22 (IL-22) production in CD4(+) T Cells by IL-17A Secreted from CpG-Stimulated Keratinocytes
por: Li, Zheng Jun, et al.
Publicado: (2016)

Interleukin-1B (IL-1B-31 and IL-1B-511) and interleukin-1 receptor antagonist (IL-1Ra) gene polymorphisms in primary immune thrombocytopenia
por: Yadav, Deependra Kumar, et al.
Publicado: (2017)

Cytokine signaling-1 suppressor is inducible by IL-1beta and inhibits the catabolic effects of IL-1beta in chondrocytes: its implication in the paradoxical joint-protective role of IL-1beta
por: Choi, Yong Seok, et al.
Publicado: (2013)

Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs
por: Neves, Fabiana, et al.
Publicado: (2015)

Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β
por: Yoo, Jihye, et al.
Publicado: (2022)

IL-1 Family Antagonists in Mouse and Human Skin Inflammation
por: Martin, Praxedis, et al.
Publicado: (2021)

Small intestinal eosinophils regulate Th17 cells by producing IL-1 receptor antagonist
por: Sugawara, Reiko, et al.
Publicado: (2016)

Hydrochloric acid-treated Bacillus subtilis ghosts induce IL-1 beta, IL-6, and TNF-alpha in murine macrophage
por: Kim, Young-Min, et al.
Publicado: (2022)

IL-1R–MyD88 signaling in keratinocyte transformation and carcinogenesis
por: Cataisson, Christophe, et al.
Publicado: (2012)

Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta- converting enzyme-mediated apoptosis
Publicado: (1996)

Comparative Roles of IL-1, IL-6, IL-10, IL-17, IL-18, 1L-22, IL-33, and IL-37 in Various Cardiovascular Diseases With Potential Insights for Targeted Immunotherapy
por: Abubakar, Muhammad, et al.
Publicado: (2023)

Assessment of IL-6, IL-8 and TNF-α levels in the gingival tissue of patients with periodontitis
por: NOH, MIN KI, et al.
Publicado: (2013)

The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes
por: Simanski, Maren, et al.
Publicado: (2016)

Yersinia pestis Activates Both IL-1β and IL-1 Receptor Antagonist to Modulate Lung Inflammation during Pneumonic Plague
por: Sivaraman, Vijay, et al.
Publicado: (2015)

Impact of IL-1β and the IL-1R antagonist on relapse risk and survival in AML patients undergoing immunotherapy for remission maintenance
por: Grauers Wiktorin, Hanna, et al.
Publicado: (2021)

Expression of IL-1 family members upon stimulation with IL-17 differs in keratinocytes derived from psoriasis patients and healthy donors
por: Muhr, P, et al.
Publicado: (2010)

IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis
por: Goldstein, Jérémie D, et al.
Publicado: (2020)

Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β
por: Ainouze, Michelle, et al.
Publicado: (2018)

8. Il-1b Antagonism Reduces Skin Scarring in Obese Mouse Wounds
por: Cotterell, Asha C., et al.
Publicado: (2023)

Association of IL33, IL1RL1, IL1RAP Polymorphisms and Asthma in Chinese Han Children
por: Wu, Maolan, et al.
Publicado: (2021)

Design of Glycoengineered IL-4 Antagonists Employing Chemical and Biosynthetic Glycosylation
por: Thomas, Sarah, et al.
Publicado: (2023)

Blood Levels of IL-Iβ, IL-6, IL-8, TNF-α, and MCP-1 in Pneumoconiosis Patients Exposed to Inorganic Dusts
por: Lee, Jong Seong, et al.
Publicado: (2009)

Recurrent poliserositis succesfully treated with IL-1 receptor antagonist Anakinra
por: Lovillo, MS Camacho, et al.
Publicado: (2011)

Production of interleukin (IL)-1 receptor antagonist by human articular chondrocytes
por: Palmer, G, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_q7sajm7tjercm7116dh6lpop8b