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IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β

Extracellular interleukin 1 alpha (IL-1α) released from keratinocytes is one of the endpoints for in vitro assessments of skin irritancy. Although cells dying via primary skin irritation undergo apoptosis as well as necrosis, IL-1α is not released in apoptotic cells. On the other hand, active secret...

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Detalles Bibliográficos
Autores principales:	Lee, Hyejin, Cheong, Kyung Ah, Kim, Ji-Young, Kim, Nan-Hyung, Noh, Minsoo, Lee, Ai-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029682/ https://www.ncbi.nlm.nih.gov/pubmed/29310426 http://dx.doi.org/10.4062/biomolther.2017.167

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