Cargando…

Molecular and Functional Characterization of Choline Transporter-Like Proteins in Esophageal Cancer Cells and Potential Therapeutic Targets

In this study, we examined the molecular and functional characterization of choline uptake in the human esophageal cancer cells. In addition, we examined the influence of various drugs on the transport of [(3)H]choline, and explored the possible correlation between the inhibition of choline uptake a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nagashima, Fumiaki, Nishiyama, Ryohta, Iwao, Beniko, Kawai, Yuiko, Ishii, Chikanao, Yamanaka, Tsuyoshi, Uchino, Hiroyuki, Inazu, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029686/ https://www.ncbi.nlm.nih.gov/pubmed/29223141 http://dx.doi.org/10.4062/biomolther.2017.113

Ejemplares similares

PT712. Functional expression of choline transporter like-protein 1 (CTL1) and CTL2 in human brain microvascular endothelial cells
por: Iwao, Beniko, et al.
Publicado: (2016)

Functional Expression of Choline Transporter-Like Protein 1 in LNCaP Prostate Cancer Cells: A Novel Molecular Target
por: Saiki, Iwao, et al.
Publicado: (2020)

Functional Expression of Choline Transporters in Microglia and Their Regulation of Microglial M1/M2 Polarization
por: Okada, Toshio, et al.
Publicado: (2022)

Functional Expression of Choline Transporters in Human Neural Stem Cells and Its Link to Cell Proliferation, Cell Viability, and Neurite Outgrowth
por: Fujita, Yosuke, et al.
Publicado: (2021)

Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells
por: Hirai, Kaho, et al.
Publicado: (2020)

Licochalcone E, a β-Amyloid Aggregation Inhibitor, Regulates Microglial M1/M2 Polarization via Inhibition of CTL1-Mediated Choline Uptake
por: Muto, Eisuke, et al.
Publicado: (2023)

Anticancer Activity of Amb4269951, a Choline Transporter-Like Protein 1 Inhibitor, in Human Glioma Cells
por: Watanabe, Saiichiro, et al.
Publicado: (2020)

Functional Expression of Choline Transporters in the Blood–Brain Barrier
por: Inazu, Masato
Publicado: (2019)

Protein kinase C promotes choline transporter-like protein 1 function via improved cell surface expression in immortalized human hepatic cells
por: Ishikawa, Takuya, et al.
Publicado: (2020)

A Novel Plant-Derived Choline Transporter-like Protein 1 Inhibitor, Amb544925, Induces Apoptotic Cell Death via the Ceramide/Survivin Pathway in Tongue Squamous Cell Carcinoma
por: Shibata, Kaoru, et al.
Publicado: (2022)

Altered choline level in atherosclerotic lesions: Upregulation of choline transporter-like protein 1 in human coronary unstable plaque
por: Nakamura, Eriko, et al.
Publicado: (2023)

Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters
por: Taylor, Adrian, et al.
Publicado: (2021)

Functional characterization of Clonorchis sinensis choline transporter
por: Won, Jeong Yeon, et al.
Publicado: (2023)

Arabidopsis choline transporter-like 1 (CTL1) regulates secretory trafficking of auxin transporters to control seedling growth
por: Wang, Yuan, et al.
Publicado: (2017)

Complete remission following pembrolizumab therapy for a patient with nephroureterectomy positive-margin carcinoma in situ and bladder cancer unresponsive to Bacille Calmette–Guérin therapy
por: Nakamura, Ryohta, et al.
Publicado: (2023)

Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids
por: Horibata, Yasuhiro, et al.
Publicado: (2021)

Choline dihydrogen phosphate
por: Fujita, Kyoko, et al.
Publicado: (2009)

Kinesin-II Is Required for Axonal Transport of Choline Acetyltransferase in Drosophila
por: Ray, Krishanu, et al.
Publicado: (1999)

Insulin Regulates the Activity of the High-Affinity Choline Transporter CHT
por: Fishwick, Katherine J., et al.
Publicado: (2015)

Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter
por: Choudhary, Parul, et al.
Publicado: (2017)

Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-α and therapeutic targeting
por: Xiong, J, et al.
Publicado: (2015)

Protective Effects of Choline against Inflammatory Cytokines and Characterization of Transport in Motor Neuron-like Cell Lines (NSC-34)
por: Latif, Sana, et al.
Publicado: (2022)

Choline transporter gene variation is associated with attention-deficit hyperactivity disorder
por: English, Brett A., et al.
Publicado: (2009)

Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila
por: Dey, Swagata, et al.
Publicado: (2018)

Anticancer Activity of the Choline Kinase Inhibitor PL48 Is Due to Selective Disruption of Choline Metabolism and Transport Systems in Cancer Cell Lines
por: García-Molina, Pablo, et al.
Publicado: (2022)

Primary lung cancer treatable with radical resection after complete remission with pembrolizumab therapy following gemcitabine and carboplatin chemotherapy for multiple metastases of bladder cancer
por: Nakamura, Ryohta, et al.
Publicado: (2022)

In silico predictive model to determine vector-mediated transport properties for the blood–brain barrier choline transporter
por: Shityakov, Sergey, et al.
Publicado: (2014)

Upregulation of the high-affinity choline transporter in colon relieves stress-induced hyperalgesia
por: Lin, Meng-Juan, et al.
Publicado: (2018)

Hepatic Choline Transport Is Inhibited During Fatty Acid–Induced Lipotoxicity and Obesity
por: O’Dwyer, Conor, et al.
Publicado: (2020)

LECITHIN SYNTHESIS, INTRACELLULAR TRANSPORT, AND SECRETION IN RAT LIVER : IV. A Radioautographic and Biochemical Study of Choline-Deficient Rats Injected with Choline-(3)H
por: Stein, Olga, et al.
Publicado: (1969)

[(99m)Tc]Tc-DTPA-Bis(cholineethylamine) as an Oncologic Tracer for the Detection of Choline Transporter (ChT) and Choline Kinase (ChK) Expression in Cancer
por: Jaswal, Ambika Parmar, et al.
Publicado: (2022)

Choline and Choline alphoscerate Do Not Modulate Inflammatory Processes in the Rat Brain
por: Tayebati, Seyed Khosrow, et al.
Publicado: (2017)

Estimated Choline Intakes and Dietary Sources of Choline in Pregnant Australian Women
por: Probst, Yasmine, et al.
Publicado: (2022)

Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis
por: Beckmann, Janet, et al.
Publicado: (2014)

Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter
por: Ennis, Elizabeth A., et al.
Publicado: (2015)

Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress
por: Zhao, Chen, et al.
Publicado: (2018)

A Cross-Sectional Study Comparing the Prevalence of Bullous Pemphigoid Autoantibodies in 275 Cases of Type II Diabetes Mellitus Treated With or Without Dipeptidyl Peptidase-IV Inhibitors
por: Izumi, Kentaro, et al.
Publicado: (2019)

Lack of the human choline transporter‐like protein SLC44A2 causes hearing impairment and a rare red blood phenotype
por: Koehl, Bérengère, et al.
Publicado: (2023)

Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations
por: Ganz, Ariel B., et al.
Publicado: (2017)

Assessment of Amino Acid/Drug Transporters for Renal Transport of [(18)F]Fluciclovine (anti-[(18)F]FACBC) in Vitro
por: Ono, Masahiro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_lmgflp5kpb9qat4ktlsa2qqfdr