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Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation

Neuronal nicotinic acetylcholine receptors (nAChRs) of the cholinergic system have been linked to antinociception, and therefore could be an alternative target for pain alleviation. nAChR activity has been shown to be regulated by the nicotinic modulator, lynx1, which forms stable complexes with nAC...

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Detalles Bibliográficos
Autores principales: Nissen, Neel I., Anderson, Kristin R., Wang, Huaixing, Lee, Hui Sun, Garrison, Carly, Eichelberger, Samantha A., Ackerman, Kasarah, Im, Wonpil, Miwa, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029753/
https://www.ncbi.nlm.nih.gov/pubmed/29969495
http://dx.doi.org/10.1371/journal.pone.0199643