Cargando…

Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation

Neuronal nicotinic acetylcholine receptors (nAChRs) of the cholinergic system have been linked to antinociception, and therefore could be an alternative target for pain alleviation. nAChR activity has been shown to be regulated by the nicotinic modulator, lynx1, which forms stable complexes with nAC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nissen, Neel I., Anderson, Kristin R., Wang, Huaixing, Lee, Hui Sun, Garrison, Carly, Eichelberger, Samantha A., Ackerman, Kasarah, Im, Wonpil, Miwa, Julie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029753/ https://www.ncbi.nlm.nih.gov/pubmed/29969495 http://dx.doi.org/10.1371/journal.pone.0199643

Ejemplares similares

Lynx1 prototoxins: critical accessory proteins of neuronal nicotinic acetylcholine receptors
por: Miwa, Julie M
Publicado: (2021)

Biophysical characterization of lynx‐nicotinic receptor interactions using atomic force microscopy
por: Pisapati, Avani V., et al.
Publicado: (2021)

Lynx Prototoxins: Roles of Endogenous Mammalian Neurotoxin-Like Proteins in Modulating Nicotinic Acetylcholine Receptor Function to Influence Complex Biological Processes
por: Miwa, Julie M., et al.
Publicado: (2019)

Deletion of lynx1 reduces the function of α6* nicotinic receptors
por: Parker, Rell L., et al.
Publicado: (2017)

Modulation of cholinergic activity through lynx prototoxins: Implications for cognition and anxiety regulation
por: Anderson, Kristin R., et al.
Publicado: (2020)

Differential Expression Patterns of Lynx Proteins and Involvement of Lynx1 in Prepulse Inhibition
por: Sherafat, Yasmine, et al.
Publicado: (2021)

Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons
por: Venkatesan, Sridevi, et al.
Publicado: (2023)

Patterns of variation in reproductive parameters in Eurasian lynx (Lynx lynx)
por: Nilsen, Erlend B., et al.
Publicado: (2011)

Update of the helminth fauna in Eurasian lynx (Lynx lynx) in Poland
por: Kołodziej-Sobocińska, Marta, et al.
Publicado: (2018)

Troglostrongylus brevior in an Eurasian lynx (Lynx lynx) from Bosnia and Herzegovina
por: Alić, Amer, et al.
Publicado: (2015)

Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine
por: Schapira, Matthieu, et al.
Publicado: (2002)

Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2′-Fluoro-3′-(substituted pyridinyl)-7-deschloroepibatidine Analogues
por: Ondachi, Pauline W., et al.
Publicado: (2014)

Enhancement in Motor Learning through Genetic Manipulation of the Lynx1 Gene
por: Miwa, Julie M., et al.
Publicado: (2012)

A retrospective study of mortality in Eurasian lynx (Lynx lynx) in UK zoos
por: Heaver, Joseph, et al.
Publicado: (2019)

Membranous glomerulonephritis in the Iberian lynx (Lynx pardinus)
por: Jiménez, Ma Ángeles, et al.
Publicado: (2008)

Landscape connectivity for bobcat (Lynx rufus) and lynx (Lynx canadensis) in the Northeastern United States
por: Farrell, Laura E., et al.
Publicado: (2018)

Spatial density estimates of Eurasian lynx (Lynx lynx) in the French Jura and Vosges Mountains
por: Gimenez, Olivier, et al.
Publicado: (2019)

Cardiomyopathy Associated With Coronary Arteriosclerosis in Free-Ranging Eurasian Lynx (Lynx lynx carpathicus)
por: Ryser-Degiorgis, Marie-Pierre, et al.
Publicado: (2020)

Complete mitochondrial genome and phylogenetic analysis of a Chinese Eurasian lynx (Lynx lynx)
por: Wu, Yuhan, et al.
Publicado: (2018)

Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors
por: Bychkov, Maxim, et al.
Publicado: (2019)

Large-Scale Genetic Structuring of a Widely Distributed Carnivore - The Eurasian Lynx (Lynx lynx)
por: Rueness, Eli K., et al.
Publicado: (2014)

In situ feeding as a new management tool to conserve orphaned Eurasian lynx (lynx lynx)
por: Premier, Joe, et al.
Publicado: (2021)

Disease threats to the endangered Iberian lynx (Lynx pardinus)
por: Millán, Javier, et al.
Publicado: (2009)

Nicotinic acetylcholine receptors and cancer
por: DANG, NINGNING, et al.
Publicado: (2016)

Role of Nicotinic Acetylcholine Receptor on Efferent Inhibition in Cochlear Hair Cell
por: Im, Gi Jung
Publicado: (2012)

Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis
por: Altamura, Gennaro, et al.
Publicado: (2018)

New Insights into Gastrointestinal and Pulmonary Parasitofauna of Wild Eurasian lynx (Lynx lynx) in the Harz Mountains of Germany
por: Segeritz, Lisa, et al.
Publicado: (2021)

ADB on LYNX
por: Pettersson, T
Publicado: (1993)

Identification of a Novel Gammaherpesvirus in Canada lynx (Lynx canadensis)
por: Hendrikse, Liam D., et al.
Publicado: (2019)

Exposure to disease agents in the endangered Iberian lynx (Lynx pardinus)
por: Roelke, Melody E., et al.
Publicado: (2007)

Microsporidia as a Potential Threat to the Iberian Lynx (Lynx pardinus)
por: Izquierdo, Fernando, et al.
Publicado: (2022)

Hepatitis E virus in the endangered Iberian lynx (Lynx pardinus)
por: Caballero‐Gómez, Javier, et al.
Publicado: (2022)

Physiologically Persistent Corpora lutea in Eurasian Lynx (Lynx lynx) – Longitudinal Ultrasound and Endocrine Examinations Intra-Vitam
por: Painer, Johanna, et al.
Publicado: (2014)

The threatening but unpredictable Sarcoptes scabiei: first deadly outbreak in the Himalayan lynx, Lynx lynx isabellinus, from Pakistan
por: Hameed, Khalid, et al.
Publicado: (2016)

Demography of a Eurasian lynx (Lynx lynx) population within a strictly protected area in Central Europe
por: Palmero, Stefano, et al.
Publicado: (2021)

High Toxocara cati prevalence in wild, free-ranging Eurasian lynx (Lynx lynx) in Finland, 1999–2015
por: Virta, Miisa, et al.
Publicado: (2022)

Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models
por: Mineev, Konstantin S., et al.
Publicado: (2020)

Management of Suspected Cases of Feline Immunodeficiency Virus Infection in Eurasian Lynx (Lynx lynx) During an International Translocation Program
por: Ryser-Degiorgis, Marie-Pierre, et al.
Publicado: (2021)

Phylogenetic analyses of Eurasian lynx (Lynx lynx Linnaeus, 1758) including new mitochondrial DNA sequences from Iran
por: Behzadi, Farshad, et al.
Publicado: (2022)

Long‐term changes in habitat selection and prey spectrum in a reintroduced Eurasian lynx (Lynx lynx) population in Switzerland
por: Nagl, Daniela, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8g265s9vajh13sj2d7p1rfcl7d