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Detection of equine atypical myopathy-associated hypoglycin A in plant material: Optimisation and validation of a novel LC-MS based method without derivatisation

Hypoglycin A (HGA) toxicity, following ingestion of material from certain plants, is linked to an acquired multiple acyl-CoA dehydrogenase deficiency known as atypical myopathy, a commonly fatal form of equine rhabdomyolysis seen worldwide. Whilst some plants are known to contain this toxin, little...

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Detalles Bibliográficos
Autores principales: González Medina, Sonia, Hyde, Carolyne, Lovera, Imogen, Piercy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029767/
https://www.ncbi.nlm.nih.gov/pubmed/29969503
http://dx.doi.org/10.1371/journal.pone.0199521