Cargando…

Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway

Human visual recognition activates a dense network of overlapping feedforward and recurrent neuronal processes, making it hard to disentangle processing in the feedforward from the feedback direction. Here, we used ultra-rapid serial visual presentation to suppress sustained activity that blurs the...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohsenzadeh, Yalda, Qin, Sheng, Cichy, Radoslaw M, Pantazis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029845/
https://www.ncbi.nlm.nih.gov/pubmed/29927384
http://dx.doi.org/10.7554/eLife.36329
_version_ 1783337037826359296
author Mohsenzadeh, Yalda
Qin, Sheng
Cichy, Radoslaw M
Pantazis, Dimitrios
author_facet Mohsenzadeh, Yalda
Qin, Sheng
Cichy, Radoslaw M
Pantazis, Dimitrios
author_sort Mohsenzadeh, Yalda
collection PubMed
description Human visual recognition activates a dense network of overlapping feedforward and recurrent neuronal processes, making it hard to disentangle processing in the feedforward from the feedback direction. Here, we used ultra-rapid serial visual presentation to suppress sustained activity that blurs the boundaries of processing steps, enabling us to resolve two distinct stages of processing with MEG multivariate pattern classification. The first processing stage was the rapid activation cascade of the bottom-up sweep, which terminated early as visual stimuli were presented at progressively faster rates. The second stage was the emergence of categorical information with peak latency that shifted later in time with progressively faster stimulus presentations, indexing time-consuming recurrent processing. Using MEG-fMRI fusion with representational similarity, we localized recurrent signals in early visual cortex. Together, our findings segregated an initial bottom-up sweep from subsequent feedback processing, and revealed the neural signature of increased recurrent processing demands for challenging viewing conditions.
format Online
Article
Text
id pubmed-6029845
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-60298452018-07-05 Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway Mohsenzadeh, Yalda Qin, Sheng Cichy, Radoslaw M Pantazis, Dimitrios eLife Neuroscience Human visual recognition activates a dense network of overlapping feedforward and recurrent neuronal processes, making it hard to disentangle processing in the feedforward from the feedback direction. Here, we used ultra-rapid serial visual presentation to suppress sustained activity that blurs the boundaries of processing steps, enabling us to resolve two distinct stages of processing with MEG multivariate pattern classification. The first processing stage was the rapid activation cascade of the bottom-up sweep, which terminated early as visual stimuli were presented at progressively faster rates. The second stage was the emergence of categorical information with peak latency that shifted later in time with progressively faster stimulus presentations, indexing time-consuming recurrent processing. Using MEG-fMRI fusion with representational similarity, we localized recurrent signals in early visual cortex. Together, our findings segregated an initial bottom-up sweep from subsequent feedback processing, and revealed the neural signature of increased recurrent processing demands for challenging viewing conditions. eLife Sciences Publications, Ltd 2018-06-21 /pmc/articles/PMC6029845/ /pubmed/29927384 http://dx.doi.org/10.7554/eLife.36329 Text en © 2018, Mohsenzadeh et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Mohsenzadeh, Yalda
Qin, Sheng
Cichy, Radoslaw M
Pantazis, Dimitrios
Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title_full Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title_fullStr Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title_full_unstemmed Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title_short Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
title_sort ultra-rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029845/
https://www.ncbi.nlm.nih.gov/pubmed/29927384
http://dx.doi.org/10.7554/eLife.36329
work_keys_str_mv AT mohsenzadehyalda ultrarapidserialvisualpresentationrevealsdynamicsoffeedforwardandfeedbackprocessesintheventralvisualpathway
AT qinsheng ultrarapidserialvisualpresentationrevealsdynamicsoffeedforwardandfeedbackprocessesintheventralvisualpathway
AT cichyradoslawm ultrarapidserialvisualpresentationrevealsdynamicsoffeedforwardandfeedbackprocessesintheventralvisualpathway
AT pantazisdimitrios ultrarapidserialvisualpresentationrevealsdynamicsoffeedforwardandfeedbackprocessesintheventralvisualpathway