Cargando…

The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran

INTRODUCTION: Human papillomavirus (HPV) infection is strongly associated with risk of cervical cancer and genital warts. AIM: The study aimed to report the prevalence of genus alpha human papillomavirus (HPV) types in women with cervical infection and/or inflammatory in Western Iran. MATERIALS AND...

Descripción completa

Detalles Bibliográficos
Autores principales: Mirbahari, Seyed Ghasem, Sadeghi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AVICENA, d.o.o., Sarajevo 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029900/
https://www.ncbi.nlm.nih.gov/pubmed/30061800
http://dx.doi.org/10.5455/msm.2018.30.113-117
_version_ 1783337043468746752
author Mirbahari, Seyed Ghasem
Sadeghi, Masoud
author_facet Mirbahari, Seyed Ghasem
Sadeghi, Masoud
author_sort Mirbahari, Seyed Ghasem
collection PubMed
description INTRODUCTION: Human papillomavirus (HPV) infection is strongly associated with risk of cervical cancer and genital warts. AIM: The study aimed to report the prevalence of genus alpha human papillomavirus (HPV) types in women with cervical infection and/or inflammatory in Western Iran. MATERIALS AND METHODS: In a cross-sectional study, 435 women were clinically diagnosed with cervical infections. The method of HPVs detection was polymerase chain reaction (PCR). The majority of patients (304 patients) did Pap smear based on liquid-based specimens. RESULTS: Out of 435 patients, 150 patients (34.5%) had HPV positivity that the prevalence of high-risk HPVs was 52.7%. Out of 76 patients with Pap smear positivity, 68.4% had atypical squamous cells of undetermined significance cytology class and 31.6% had low-grade squamous intraepithelial lesion cytology class. The most prevalence rate of HPV was in age ≤30 years. HPV 16 and HPV 56 were the most prevalence rate among high-risk HPVs. Overall HPV alpha-10 (59%) and HPV alpha-9 (32.2%) had the most prevalence rate. CONCLUSIONS: Among high-risk HPVs, HPV 16 was the most common HPV detected in our population with a very low prevalence of HPV 18. In addition, HPV 6 and then HPV 11 had the most prevalence rate in the women with uterine cervix (cervical) infection among low-risk HPVs.
format Online
Article
Text
id pubmed-6029900
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher AVICENA, d.o.o., Sarajevo
record_format MEDLINE/PubMed
spelling pubmed-60299002018-07-30 The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran Mirbahari, Seyed Ghasem Sadeghi, Masoud Mater Sociomed Original Paper INTRODUCTION: Human papillomavirus (HPV) infection is strongly associated with risk of cervical cancer and genital warts. AIM: The study aimed to report the prevalence of genus alpha human papillomavirus (HPV) types in women with cervical infection and/or inflammatory in Western Iran. MATERIALS AND METHODS: In a cross-sectional study, 435 women were clinically diagnosed with cervical infections. The method of HPVs detection was polymerase chain reaction (PCR). The majority of patients (304 patients) did Pap smear based on liquid-based specimens. RESULTS: Out of 435 patients, 150 patients (34.5%) had HPV positivity that the prevalence of high-risk HPVs was 52.7%. Out of 76 patients with Pap smear positivity, 68.4% had atypical squamous cells of undetermined significance cytology class and 31.6% had low-grade squamous intraepithelial lesion cytology class. The most prevalence rate of HPV was in age ≤30 years. HPV 16 and HPV 56 were the most prevalence rate among high-risk HPVs. Overall HPV alpha-10 (59%) and HPV alpha-9 (32.2%) had the most prevalence rate. CONCLUSIONS: Among high-risk HPVs, HPV 16 was the most common HPV detected in our population with a very low prevalence of HPV 18. In addition, HPV 6 and then HPV 11 had the most prevalence rate in the women with uterine cervix (cervical) infection among low-risk HPVs. AVICENA, d.o.o., Sarajevo 2018-06 /pmc/articles/PMC6029900/ /pubmed/30061800 http://dx.doi.org/10.5455/msm.2018.30.113-117 Text en © 2018 Seyed Ghasem Mirbahari, Masoud Sadeghi http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Mirbahari, Seyed Ghasem
Sadeghi, Masoud
The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title_full The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title_fullStr The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title_full_unstemmed The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title_short The Prevalence of Genus Alpha Human Papillomavirus in Women with Uterine Cervical Infection and/or Inflammation in Western Iran
title_sort prevalence of genus alpha human papillomavirus in women with uterine cervical infection and/or inflammation in western iran
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029900/
https://www.ncbi.nlm.nih.gov/pubmed/30061800
http://dx.doi.org/10.5455/msm.2018.30.113-117
work_keys_str_mv AT mirbahariseyedghasem theprevalenceofgenusalphahumanpapillomavirusinwomenwithuterinecervicalinfectionandorinflammationinwesterniran
AT sadeghimasoud theprevalenceofgenusalphahumanpapillomavirusinwomenwithuterinecervicalinfectionandorinflammationinwesterniran
AT mirbahariseyedghasem prevalenceofgenusalphahumanpapillomavirusinwomenwithuterinecervicalinfectionandorinflammationinwesterniran
AT sadeghimasoud prevalenceofgenusalphahumanpapillomavirusinwomenwithuterinecervicalinfectionandorinflammationinwesterniran