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A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Dermatological Association; The Korean Society for Investigative Dermatology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029963/ https://www.ncbi.nlm.nih.gov/pubmed/30065588 http://dx.doi.org/10.5021/ad.2018.30.4.462 |
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author | Giuseppe, Pistone Nicola, Pardo Valentina, Caputo Elena, Castelli Salvatrice, Curiale Rosario, Gurreri Rita, Bongiorno Maria |
author_facet | Giuseppe, Pistone Nicola, Pardo Valentina, Caputo Elena, Castelli Salvatrice, Curiale Rosario, Gurreri Rita, Bongiorno Maria |
author_sort | Giuseppe, Pistone |
collection | PubMed |
description | Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab. |
format | Online Article Text |
id | pubmed-6029963 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Dermatological Association; The Korean Society for Investigative Dermatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-60299632018-08-01 A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab Giuseppe, Pistone Nicola, Pardo Valentina, Caputo Elena, Castelli Salvatrice, Curiale Rosario, Gurreri Rita, Bongiorno Maria Ann Dermatol Case Report Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2018-08 2018-06-27 /pmc/articles/PMC6029963/ /pubmed/30065588 http://dx.doi.org/10.5021/ad.2018.30.4.462 Text en Copyright © 2018 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Giuseppe, Pistone Nicola, Pardo Valentina, Caputo Elena, Castelli Salvatrice, Curiale Rosario, Gurreri Rita, Bongiorno Maria A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title | A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title_full | A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title_fullStr | A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title_full_unstemmed | A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title_short | A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab |
title_sort | case of moderate hidradenitis suppurativa and psoriasis treated with secukinumab |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029963/ https://www.ncbi.nlm.nih.gov/pubmed/30065588 http://dx.doi.org/10.5021/ad.2018.30.4.462 |
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