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A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab

Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with...

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Autores principales: Giuseppe, Pistone, Nicola, Pardo, Valentina, Caputo, Elena, Castelli, Salvatrice, Curiale, Rosario, Gurreri, Rita, Bongiorno Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029963/
https://www.ncbi.nlm.nih.gov/pubmed/30065588
http://dx.doi.org/10.5021/ad.2018.30.4.462
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author Giuseppe, Pistone
Nicola, Pardo
Valentina, Caputo
Elena, Castelli
Salvatrice, Curiale
Rosario, Gurreri
Rita, Bongiorno Maria
author_facet Giuseppe, Pistone
Nicola, Pardo
Valentina, Caputo
Elena, Castelli
Salvatrice, Curiale
Rosario, Gurreri
Rita, Bongiorno Maria
author_sort Giuseppe, Pistone
collection PubMed
description Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab.
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spelling pubmed-60299632018-08-01 A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab Giuseppe, Pistone Nicola, Pardo Valentina, Caputo Elena, Castelli Salvatrice, Curiale Rosario, Gurreri Rita, Bongiorno Maria Ann Dermatol Case Report Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2018-08 2018-06-27 /pmc/articles/PMC6029963/ /pubmed/30065588 http://dx.doi.org/10.5021/ad.2018.30.4.462 Text en Copyright © 2018 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Giuseppe, Pistone
Nicola, Pardo
Valentina, Caputo
Elena, Castelli
Salvatrice, Curiale
Rosario, Gurreri
Rita, Bongiorno Maria
A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title_full A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title_fullStr A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title_full_unstemmed A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title_short A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
title_sort case of moderate hidradenitis suppurativa and psoriasis treated with secukinumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029963/
https://www.ncbi.nlm.nih.gov/pubmed/30065588
http://dx.doi.org/10.5021/ad.2018.30.4.462
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