LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling

Numerous findings have demonstrated that long noncoding RNA (lncRNA) dysregulation plays a key role in many human neoplasms, including tongue squamous cell carcinoma (TSCC), yet the potential mechanisms of lncRNAs in chemo-resistance remain elusive. Our research showed that the lncRNA KCNQ1OT1 was u...

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Detalles Bibliográficos
Autores principales: Zhang, Shanyi, Ma, Hanyu, Zhang, Daming, Xie, Shule, Wang, Weiwei, Li, Qunxing, Lin, Zhaoyu, Wang, Youyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030066/
https://www.ncbi.nlm.nih.gov/pubmed/29970910
http://dx.doi.org/10.1038/s41419-018-0793-5

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