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An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

The microRNA-34a is a well-studied tumor suppressor microRNA (miRNA) and a direct downstream target of TP53 with roles in several pathways associated with oncogenesis, such as proliferation, cellular growth, and differentiation. Due to its broad tumor suppressive activity, it is not surprising that...

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Detalles Bibliográficos
Autores principales: Serviss, Jason T., Andrews, Nathanael, Van den Eynden, Jimmy, Richter, Felix Clemens, Houtman, Miranda, Vesterlund, Mattias, Schwarzmueller, Laura, Johnsson, Per, Larsson, Erik, Grandér †, Dan, Pokrovskaja Tamm, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030072/
https://www.ncbi.nlm.nih.gov/pubmed/29970884
http://dx.doi.org/10.1038/s41419-018-0777-5

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