Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

Drug resistance is a leading cause for treatment failure in many cancers, including neuroblastoma, the most common solid extracranial childhood malignancy. Previous studies from our lab indicate that histone deacetylase 10 (HDAC10) is important for the homeostasis of lysosomes, i.e. acidic vesicular...

Descripción completa

Detalles Bibliográficos
Autores principales: Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne, Witt, Olaf, Oehme, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030077/
https://www.ncbi.nlm.nih.gov/pubmed/29968769
http://dx.doi.org/10.1038/s41598-018-28265-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030077/
https://www.ncbi.nlm.nih.gov/pubmed/29968769
http://dx.doi.org/10.1038/s41598-018-28265-5

Ejemplares similares