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Motor-like DNA motion due to an ATP-hydrolyzing protein under nanoconfinement
We report that long double-stranded DNA confined to quasi-1D nanochannels undergoes superdiffusive motion under the action of the enzyme T4 DNA ligase in the presence of necessary co-factors. Inside the confined environment of the nanochannel, double-stranded DNA molecules stretch out due to self-av...
Autores principales: | Roushan, Maedeh, Azad, Zubair, Movahed, Saeid, Ray, Paul D., Livshits, Gideon I., Lim, Shuang Fang, Weninger, Keith R., Riehn, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030079/ https://www.ncbi.nlm.nih.gov/pubmed/29968756 http://dx.doi.org/10.1038/s41598-018-28278-0 |
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